TY - JOUR
T1 - Remission of loss of control eating and changes in components of the metabolic syndrome
AU - Shank, Lisa M.
AU - Tanofsky-Kraff, Marian
AU - Radin, Rachel M.
AU - Shomaker, Lauren B.
AU - Wilfley, Denise E.
AU - Young, Jami F.
AU - Brady, Sheila
AU - Olsen, Cara H.
AU - Reynolds, James C.
AU - Yanovski, Jack A.
N1 - Funding Information:
Support for this project was provided by the following funding sources: NIDDK 1R01DK080906 (to MTK), USUHS grant R072IC (to M.T.-K.), and NICHD Intramural Research Program ZIA-HO-00641 (to J.A.Y.). No funding sources had any role in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the paper for publication. J.A.Y. is a Commissioned Officer of the United States Public Health Service (USPHS). The opinions and assertions expressed herein are those of the authors and are not to be construed as reflecting the views of the USPHS, the Department of the Navy, USUHS or the U.S. Department of Defense.
Funding Information:
NIDDK, Grant Number: 1R01DK080906; USUHS, Grant Number: R072IC; NICHD Intramural Research Program, Grant Number: ZIA-HO-00641
Funding Information:
Support for this project was provided by the following funding sources: NIDDK 1R01DK080906 (to MTK), USUHS grant R072IC (to M.T.-K.), and NICHD Intramural Research Program ZIA-HO-00641 (to J.A. Y.). No funding sources had any role in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the paper for publication. J.A.Y. is a Commissioned Officer of the United States Public Health Service (USPHS). The opinions and assertions expressed herein are those of the authors and are not to be construed as reflecting the views of the USPHS, the Department of the Navy, USUHS or the U.S. Department of Defense.
Publisher Copyright:
© 2018 Wiley Periodicals, Inc.
PY - 2018/6
Y1 - 2018/6
N2 - Objective: Pediatric loss of control (LOC) eating prospectively predicts the worsening of metabolic syndrome components. However, it is unknown if remission of LOC eating is associated with improvements in metabolic health. Therefore, we conducted a secondary analysis of a trial that enrolled adolescent girls with LOC eating, examining whether LOC remission (vs. persistence) at end-of-treatment was associated with changes in metabolic syndrome components at 6-month follow-up. Method: One hundred three adolescent girls (age 14.5 ± 1.7 years; BMI-z 1.5 ± 0.3; 56.3% non-Hispanic White, 24.3% non-Hispanic Black) with elevated weight (75th–97th BMI %ile) and reported LOC eating were assessed for metabolic syndrome components at baseline and again six months following the interventions. The main effects of LOC status at end-of-treatment (persistence vs. remission) on metabolic syndrome components (waist circumference, lipids, glucose, and blood pressure) at 6-month follow-up were examined, adjusting for baseline age, depressive symptoms, LOC frequency, fat mass, and height, as well as race, change in height, change in fat mass, and the baseline value of each respective component. Results: Youth with LOC remission at end-of-treatment had lower glucose (83.9 ± 6.4 vs. 86.5 ± 5.8 mg/dL; p =.02), higher high-density lipoprotein cholesterol (50.3 ± 11.8 vs. 44.8 ± 11.9 mg/dL; p =.01), and lower triglycerides (84.4 ± 46.2 vs. 96.9 ± 53.7 mg/dL; p =.02) at 6-month follow-up when compared with youth with persistent LOC, despite no baseline differences in these components. No other component significantly differed by LOC eating status (ps >.05). Discussion: Reducing LOC eating in adolescent girls may have a beneficial impact on some components of the metabolic syndrome.
AB - Objective: Pediatric loss of control (LOC) eating prospectively predicts the worsening of metabolic syndrome components. However, it is unknown if remission of LOC eating is associated with improvements in metabolic health. Therefore, we conducted a secondary analysis of a trial that enrolled adolescent girls with LOC eating, examining whether LOC remission (vs. persistence) at end-of-treatment was associated with changes in metabolic syndrome components at 6-month follow-up. Method: One hundred three adolescent girls (age 14.5 ± 1.7 years; BMI-z 1.5 ± 0.3; 56.3% non-Hispanic White, 24.3% non-Hispanic Black) with elevated weight (75th–97th BMI %ile) and reported LOC eating were assessed for metabolic syndrome components at baseline and again six months following the interventions. The main effects of LOC status at end-of-treatment (persistence vs. remission) on metabolic syndrome components (waist circumference, lipids, glucose, and blood pressure) at 6-month follow-up were examined, adjusting for baseline age, depressive symptoms, LOC frequency, fat mass, and height, as well as race, change in height, change in fat mass, and the baseline value of each respective component. Results: Youth with LOC remission at end-of-treatment had lower glucose (83.9 ± 6.4 vs. 86.5 ± 5.8 mg/dL; p =.02), higher high-density lipoprotein cholesterol (50.3 ± 11.8 vs. 44.8 ± 11.9 mg/dL; p =.01), and lower triglycerides (84.4 ± 46.2 vs. 96.9 ± 53.7 mg/dL; p =.02) at 6-month follow-up when compared with youth with persistent LOC, despite no baseline differences in these components. No other component significantly differed by LOC eating status (ps >.05). Discussion: Reducing LOC eating in adolescent girls may have a beneficial impact on some components of the metabolic syndrome.
KW - adolescents
KW - loss of control eating
KW - metabolic syndrome
KW - obesity
KW - overweight
UR - http://www.scopus.com/inward/record.url?scp=85044642426&partnerID=8YFLogxK
U2 - 10.1002/eat.22866
DO - 10.1002/eat.22866
M3 - Article
C2 - 29607525
AN - SCOPUS:85044642426
SN - 0276-3478
VL - 51
SP - 565
EP - 573
JO - International Journal of Eating Disorders
JF - International Journal of Eating Disorders
IS - 6
ER -