Reversible dilated cardiomyopathy related to amphotericin B therapy

Patrick J. Danaher*, Michael K. Cao, Gregory M. Anstead, Matthew J. Dolan, Caroline C. DeWitt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


We describe a patient who developed dilated cardiomyopathy and clinical congestive heart failure after 2 months of therapy with amphotericin B (AmB) for disseminated coccidioidomycosis. His echocardiographic abnormalities and heart failure resolved after posaconazole was substituted for AmB. It is important to recognize the rare and potentially reversible toxicity of AmB.

Original languageEnglish
Pages (from-to)115-117
Number of pages3
JournalJournal of Antimicrobial Chemotherapy
Issue number1
StatePublished - Jan 2004
Externally publishedYes


  • Coccidioides immitis
  • Coccidioidomycosis
  • Posaconazole


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