Reversible sideroblastic anemia associated with the tetracycline analogue COL-3

Michelle A. Rudek; McDonald Horne; William D. Figg; William Dahut; Valerie Dyer; James M. Pluda; Eddie Reed

doi:10.1002/ajh.1076

Reversible sideroblastic anemia associated with the tetracycline analogue COL-3

Michelle A. Rudek, McDonald Horne, William D. Figg^*, William Dahut, Valerie Dyer, James M. Pluda, Eddie Reed

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Eight of 35 patients with cancer receiving COL-3, a tetracycline derivative with antiangiogenic properties, developed anemia while on treatment. All of these patients were enrolled on an approved Phase I clinical trial at the National Cancer Institute. Three of these patients had bone marrow examinations that revealed ringed sideroblasts. This paper describes these cases.

Original language	English
Pages (from-to)	51-53
Number of pages	3
Journal	American Journal of Hematology
Volume	67
Issue number	1
DOIs	https://doi.org/10.1002/ajh.1076
State	Published - 2001
Externally published	Yes

Keywords

Anemia
COL-3
Cancer
Phase I
Sideroblast
Tetracycline

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10.1002/ajh.1076

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title = "Reversible sideroblastic anemia associated with the tetracycline analogue COL-3",

abstract = "Eight of 35 patients with cancer receiving COL-3, a tetracycline derivative with antiangiogenic properties, developed anemia while on treatment. All of these patients were enrolled on an approved Phase I clinical trial at the National Cancer Institute. Three of these patients had bone marrow examinations that revealed ringed sideroblasts. This paper describes these cases.",

keywords = "Anemia, COL-3, Cancer, Phase I, Sideroblast, Tetracycline",

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AU - Horne, McDonald

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AU - Dahut, William

AU - Dyer, Valerie

AU - Pluda, James M.

AU - Reed, Eddie

PY - 2001

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N2 - Eight of 35 patients with cancer receiving COL-3, a tetracycline derivative with antiangiogenic properties, developed anemia while on treatment. All of these patients were enrolled on an approved Phase I clinical trial at the National Cancer Institute. Three of these patients had bone marrow examinations that revealed ringed sideroblasts. This paper describes these cases.

AB - Eight of 35 patients with cancer receiving COL-3, a tetracycline derivative with antiangiogenic properties, developed anemia while on treatment. All of these patients were enrolled on an approved Phase I clinical trial at the National Cancer Institute. Three of these patients had bone marrow examinations that revealed ringed sideroblasts. This paper describes these cases.

KW - Anemia

KW - COL-3

KW - Cancer

KW - Phase I

KW - Sideroblast

KW - Tetracycline

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JO - American Journal of Hematology

JF - American Journal of Hematology

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Reversible sideroblastic anemia associated with the tetracycline analogue COL-3

Abstract

Keywords

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