RPPA: Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology

Emanuel Petricoin; Julie Wulfkuhle; Marissa Howard; Marielena Pierobon; Virginia Espina; Alessandra Luchini; Lance A. Liotta

doi:10.1007/978-981-32-9755-5_1

RPPA: Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology

Emanuel Petricoin, Julie Wulfkuhle, Marissa Howard, Marielena Pierobon, Virginia Espina, Alessandra Luchini, Lance A. Liotta^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

13 Scopus citations

Abstract

RPPA technology has graduated from a research tool to an essential component of clinical drug discovery research and personalized medicine. Next generations of RPPA technology will be a single clinical instrument that integrates all the steps of the workflow.

Original language	English
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer
Pages	1-19
Number of pages	19
DOIs	https://doi.org/10.1007/978-981-32-9755-5_1
State	Published - 2019
Externally published	Yes

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1188
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

Keywords

Biomarkers
Drug discovery
Integrative genomics
RPPA
Reverse-phase protein array
Technology

Access to Document

10.1007/978-981-32-9755-5_1

Cite this

Petricoin, E., Wulfkuhle, J., Howard, M., Pierobon, M., Espina, V., Luchini, A., & Liotta, L. A. (2019). RPPA: Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology. In Advances in Experimental Medicine and Biology (pp. 1-19). (Advances in Experimental Medicine and Biology; Vol. 1188). Springer. https://doi.org/10.1007/978-981-32-9755-5_1

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keywords = "Biomarkers, Drug discovery, Integrative genomics, RPPA, Reverse-phase protein array, Technology",

author = "Emanuel Petricoin and Julie Wulfkuhle and Marissa Howard and Marielena Pierobon and Virginia Espina and Alessandra Luchini and Liotta, {Lance A.}",

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RPPA: Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology. / Petricoin, Emanuel; Wulfkuhle, Julie; Howard, Marissa et al.
Advances in Experimental Medicine and Biology. Springer, 2019. p. 1-19 (Advances in Experimental Medicine and Biology; Vol. 1188).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - RPPA

T2 - Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology

AU - Petricoin, Emanuel

AU - Wulfkuhle, Julie

AU - Howard, Marissa

AU - Pierobon, Marielena

AU - Espina, Virginia

AU - Luchini, Alessandra

AU - Liotta, Lance A.

N1 - Publisher Copyright: © Springer Nature Singapore Pte Ltd 2019.

PY - 2019

Y1 - 2019

N2 - RPPA technology has graduated from a research tool to an essential component of clinical drug discovery research and personalized medicine. Next generations of RPPA technology will be a single clinical instrument that integrates all the steps of the workflow.

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KW - Drug discovery

KW - Integrative genomics

KW - RPPA

KW - Reverse-phase protein array

KW - Technology

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T3 - Advances in Experimental Medicine and Biology

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EP - 19

BT - Advances in Experimental Medicine and Biology

PB - Springer

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RPPA: Origins, Transition to a Validated Clinical Research Tool, and Next Generations of the Technology

Abstract

Publication series

Keywords

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