Serologic and molecular detection of Ehrlichia chaffeensis and Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in Korean patients

Eun jeong Heo; Jin ho Park; Ja ryong Koo; Man suk Park; Mi yeoun Park; J. Stephen Dumler; Joon seok Chae

doi:10.1128/JCM.40.8.3082-3085.2002

Serologic and molecular detection of Ehrlichia chaffeensis and Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in Korean patients

Eun jeong Heo, Jin ho Park, Ja ryong Koo, Man suk Park, Mi yeoun Park, J. Stephen Dumler, Joon seok Chae^*

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

Sera from 491 Korean patients with acute febrile diseases were tested for Ehrlichia chaffeensis and Anaplasma phagocytophila antibodies by indirect immunofluorescence assay (IFA), Western blotting, and TaqMan realtime PCR. Overall, 0.4% of sera reacted with E. chaffeensis, and 1.8% reacted with A. phagocytophila in IFAs. This is the first report of detection of antibodies to A. phagocytophila and E. chaffeensis in Korea and suggests the presence of A. phagocytophila and E. chaffeensis or antigenically similar species.

Original language	English
Pages (from-to)	3082-3085
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	40
Issue number	8
DOIs	https://doi.org/10.1128/JCM.40.8.3082-3085.2002
State	Published - 1 Aug 2002

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10.1128/JCM.40.8.3082-3085.2002

Cite this

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title = "Serologic and molecular detection of Ehrlichia chaffeensis and Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in Korean patients",

abstract = "Sera from 491 Korean patients with acute febrile diseases were tested for Ehrlichia chaffeensis and Anaplasma phagocytophila antibodies by indirect immunofluorescence assay (IFA), Western blotting, and TaqMan realtime PCR. Overall, 0.4% of sera reacted with E. chaffeensis, and 1.8% reacted with A. phagocytophila in IFAs. This is the first report of detection of antibodies to A. phagocytophila and E. chaffeensis in Korea and suggests the presence of A. phagocytophila and E. chaffeensis or antigenically similar species.",

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T1 - Serologic and molecular detection of Ehrlichia chaffeensis and Anaplasma phagocytophila (human granulocytic ehrlichiosis agent) in Korean patients

AU - Heo, Eun jeong

AU - Park, Jin ho

AU - Koo, Ja ryong

AU - Park, Man suk

AU - Park, Mi yeoun

AU - Dumler, J. Stephen

AU - Chae, Joon seok

PY - 2002/8/1

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AB - Sera from 491 Korean patients with acute febrile diseases were tested for Ehrlichia chaffeensis and Anaplasma phagocytophila antibodies by indirect immunofluorescence assay (IFA), Western blotting, and TaqMan realtime PCR. Overall, 0.4% of sera reacted with E. chaffeensis, and 1.8% reacted with A. phagocytophila in IFAs. This is the first report of detection of antibodies to A. phagocytophila and E. chaffeensis in Korea and suggests the presence of A. phagocytophila and E. chaffeensis or antigenically similar species.

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