TY - JOUR
T1 - Sexual functioning among testicular cancer survivors
T2 - A case-control study in the U.S.
AU - Kim, Christopher
AU - McGlynn, Katherine A.
AU - McCorkle, Ruth
AU - Li, Yonghong
AU - Erickson, Ralph L.
AU - Ma, Shuangge
AU - Niebuhr, David W.
AU - Zhang, Guangsheng
AU - Zhang, Yaqun
AU - Bai, Yana
AU - Dai, Li
AU - Graubard, Barry I.
AU - Zheng, Tongzhang
AU - Aschebrook-Kilfoy, Briseis
AU - Barry, Kathryn H.
AU - Zhang, Yawei
N1 - Funding Information:
This study is supported by grants CA105666 and CA130110 from the National Cancer Institute (NCI) and by Fogarty training grants 1D43TW008323-01 and 1D43TW007864-01 from the National Institute of Health (NIH) . This publication was made possible by CTSA Grant number UL1 RR024139 from the National Center for Research Resources (NCRR) , a component of the NIH and NHL roadmap for medical Research. Its content is solely the responsibility of the authors and do not necessarily represent the official view of NCRR. The authors are greatly indebted to the Study participants, without whom, there would have been no study.
PY - 2012/7
Y1 - 2012/7
N2 - Objective: Sexual function among testicular cancer survivors is a concern because affected men are of reproductive age when diagnosed. We conducted a case-control study among United States military men to examine whether testicular cancer survivors experienced impaired sexual function. Methods: A total of 246 testicular cancer cases and 236 ethnicity and age matched controls were enrolled in the study in 2008-2009. The Brief Male Sexual Function Inventory (BMSFI) was used to assess sexual function. Results: Compared to controls, cases scored significantly lower on sex drive (5.77 vs. 5.18), erection (9.40 vs. 8.63), ejaculation (10.83 vs. 9.90), and problem assessment (10.55 vs. 9.54). Cases were significantly more likely to have impaired erection (OR 1.72; 95% CI 1.11-2.64), ejaculation (OR 2.27; 95% CI 1.32-3.91), and problem assessment (OR 2.36; 95% CI 1.43-3.90). In histology and treatment analysis, nonseminoma, chemotherapy and radiation treated cases risk of erectile dysfunction, delayed ejaculation, and/or problem assessment were greater when compared to controls. Conclusion: This study provides evidence that testicular cancer survivors are more likely to have impaired sexual functioning compared to demographically matched controls. The observed impaired sexual functioning appeared to vary by treatment regimen and histologic subtype.
AB - Objective: Sexual function among testicular cancer survivors is a concern because affected men are of reproductive age when diagnosed. We conducted a case-control study among United States military men to examine whether testicular cancer survivors experienced impaired sexual function. Methods: A total of 246 testicular cancer cases and 236 ethnicity and age matched controls were enrolled in the study in 2008-2009. The Brief Male Sexual Function Inventory (BMSFI) was used to assess sexual function. Results: Compared to controls, cases scored significantly lower on sex drive (5.77 vs. 5.18), erection (9.40 vs. 8.63), ejaculation (10.83 vs. 9.90), and problem assessment (10.55 vs. 9.54). Cases were significantly more likely to have impaired erection (OR 1.72; 95% CI 1.11-2.64), ejaculation (OR 2.27; 95% CI 1.32-3.91), and problem assessment (OR 2.36; 95% CI 1.43-3.90). In histology and treatment analysis, nonseminoma, chemotherapy and radiation treated cases risk of erectile dysfunction, delayed ejaculation, and/or problem assessment were greater when compared to controls. Conclusion: This study provides evidence that testicular cancer survivors are more likely to have impaired sexual functioning compared to demographically matched controls. The observed impaired sexual functioning appeared to vary by treatment regimen and histologic subtype.
KW - Military men
KW - Sexual function
KW - Testicular cancer
UR - http://www.scopus.com/inward/record.url?scp=84862191719&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychores.2012.02.011
DO - 10.1016/j.jpsychores.2012.02.011
M3 - Article
C2 - 22691563
AN - SCOPUS:84862191719
SN - 0022-3999
VL - 73
SP - 68
EP - 73
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
IS - 1
ER -