Should genomic testing be considered in hyperlipidemia?

In patients with dyslipidemia, collect a detailed history including three-generation pedigree focused on identifying cardiovascular risk factors. Physical examination: look for xanthomas and corneal arcus. Laboratory examination: rule out nephrotic syndrome, thyroid and liver disease, and order full lipoprotein panel. Patients with FHBL may not absorb fat soluble vitamins (E and A) and may be unable to adequately absorb or transport fats/cholesterol increasing their risk of fatty liver. If uncontrolled triglycerides, consider bile acid sequestrants; if high LDL-C, add statin and PCSK9 inhibitor. Consider genetic testing and referral to genetic counseling services to assist the patient to understand his condition and discuss how and when to inform family members (Santos et al., 2016; American College of Cardiology, 2015). Point of Care Resources that can be used for patients with hyperlipidemia: c www.mdcalc.com (Hypercholesterolemia calculators: MedPed, Simon Broome, Dutch Lipid Clinic) c www.lipid.org (National Lipid Association) c www.acc.org and 2013 ACC/AHA criteria.