SJS/TEN 2019: From science to translation

Wan Chun Chang; Riichiro Abe; Paul Anderson; Wanpen Anderson; Michael R. Ardern-Jones; Thomas M. Beachkofsky; Teresa Bellón; Agnieszka K. Biala; Charles Bouchard; Gianpiero L. Cavalleri; Nicole Chapman; James Chodosh; Hyon K. Choi; Ricardo R. Cibotti; Sherrie J. Divito; Karen Dewar; Ulrike Dehaeck; Mahyar Etminan; Diane Forbes; Esther Fuchs; Jennifer L. Goldman; James H. Holmes; Elyse A. Hope; Shuen Iu Hung; Chia Ling Hsieh; Alfonso Iovieno; Julienne Jagdeo; Mee Kum Kim; David M. Koelle; Mario E. Lacouture; Sophie Le Pallec; Rannakoe J. Lehloenya; Robyn Lim; Angie Lowe; Jean McCawley; Julie McCawley; Robert G. Micheletti; Maja Mockenhaupt; Katie Niemeyer; Michael A. Norcross; Douglas Oboh; Cristina Olteanu; Helena B. Pasieka; Jonathan Peter; Munir Pirmohamed; Michael Rieder; Hajirah N. Saeed; Neil H. Shear; Christine Shieh; Sabine Straus; Chonlaphat Sukasem; Cynthia Sung; Jason A. Trubiano; Sheng Ying Tsou; Mayumi Ueta; Simona Volpi; Chen Wan; Hongsheng Wang; Zhao Qing Wang; Jessica Weintraub; Cindy Whale; Lisa M. Wheatley; Sonia Whyte-Croasdaile; Kristina B. Williams; Galen Wright; Sonia N. Yeung; Li Zhou; Wen Hung Chung; Elizabeth J. Phillips; Bruce C. Carleton

doi:10.1016/j.jdermsci.2020.02.003

SJS/TEN 2019: From science to translation

Wan Chun Chang, Riichiro Abe, Paul Anderson, Wanpen Anderson, Michael R. Ardern-Jones, Thomas M. Beachkofsky, Teresa Bellón, Agnieszka K. Biala, Charles Bouchard, Gianpiero L. Cavalleri, Nicole Chapman, James Chodosh, Hyon K. Choi, Ricardo R. Cibotti, Sherrie J. Divito, Karen Dewar, Ulrike Dehaeck, Mahyar Etminan, Diane Forbes, Esther FuchsJennifer L. Goldman, James H. Holmes, Elyse A. Hope, Shuen Iu Hung, Chia Ling Hsieh, Alfonso Iovieno, Julienne Jagdeo, Mee Kum Kim, David M. Koelle, Mario E. Lacouture, Sophie Le Pallec, Rannakoe J. Lehloenya, Robyn Lim, Angie Lowe, Jean McCawley, Julie McCawley, Robert G. Micheletti, Maja Mockenhaupt, Katie Niemeyer, Michael A. Norcross, Douglas Oboh, Cristina Olteanu, Helena B. Pasieka, Jonathan Peter, Munir Pirmohamed, Michael Rieder, Hajirah N. Saeed, Neil H. Shear, Christine Shieh, Sabine Straus, Chonlaphat Sukasem, Cynthia Sung, Jason A. Trubiano, Sheng Ying Tsou, Mayumi Ueta, Simona Volpi, Chen Wan, Hongsheng Wang, Zhao Qing Wang, Jessica Weintraub, Cindy Whale, Lisa M. Wheatley, Sonia Whyte-Croasdaile, Kristina B. Williams, Galen Wright, Sonia N. Yeung, Li Zhou, Wen Hung Chung^*, Elizabeth J. Phillips^*, Bruce C. Carleton^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

50 Scopus citations

Abstract

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26–27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.

Original language	English
Pages (from-to)	2-12
Number of pages	11
Journal	Journal of Dermatological Science
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/j.jdermsci.2020.02.003
State	Published - Apr 2020
Externally published	Yes

Keywords

Human leukocyte antigen (HLA)
Pharmacogenomics
Pharmacovigilance
Severe cutaneous adverse reaction (SCAR)
Stevens-Johnson syndrome (SJS)
Toxic epidermal necrolysis (TEN)

Access to Document

10.1016/j.jdermsci.2020.02.003

Cite this

Chang, W. C., Abe, R., Anderson, P., Anderson, W., Ardern-Jones, M. R., Beachkofsky, T. M., Bellón, T., Biala, A. K., Bouchard, C., Cavalleri, G. L., Chapman, N., Chodosh, J., Choi, H. K., Cibotti, R. R., Divito, S. J., Dewar, K., Dehaeck, U., Etminan, M., Forbes, D., ... Carleton, B. C. (2020). SJS/TEN 2019: From science to translation. Journal of Dermatological Science, 98(1), 2-12. https://doi.org/10.1016/j.jdermsci.2020.02.003

@article{aa2f962f5c0e4c59a25a89b0ba929dbf,

title = "SJS/TEN 2019: From science to translation",

abstract = "Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26–27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.",

keywords = "Human leukocyte antigen (HLA), Pharmacogenomics, Pharmacovigilance, Severe cutaneous adverse reaction (SCAR), Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN)",

author = "Chang, {Wan Chun} and Riichiro Abe and Paul Anderson and Wanpen Anderson and Ardern-Jones, {Michael R.} and Beachkofsky, {Thomas M.} and Teresa Bell{\'o}n and Biala, {Agnieszka K.} and Charles Bouchard and Cavalleri, {Gianpiero L.} and Nicole Chapman and James Chodosh and Choi, {Hyon K.} and Cibotti, {Ricardo R.} and Divito, {Sherrie J.} and Karen Dewar and Ulrike Dehaeck and Mahyar Etminan and Diane Forbes and Esther Fuchs and Goldman, {Jennifer L.} and Holmes, {James H.} and Hope, {Elyse A.} and Hung, {Shuen Iu} and Hsieh, {Chia Ling} and Alfonso Iovieno and Julienne Jagdeo and Kim, {Mee Kum} and Koelle, {David M.} and Lacouture, {Mario E.} and {Le Pallec}, Sophie and Lehloenya, {Rannakoe J.} and Robyn Lim and Angie Lowe and Jean McCawley and Julie McCawley and Micheletti, {Robert G.} and Maja Mockenhaupt and Katie Niemeyer and Norcross, {Michael A.} and Douglas Oboh and Cristina Olteanu and Pasieka, {Helena B.} and Jonathan Peter and Munir Pirmohamed and Michael Rieder and Saeed, {Hajirah N.} and Shear, {Neil H.} and Christine Shieh and Sabine Straus and Chonlaphat Sukasem and Cynthia Sung and Trubiano, {Jason A.} and Tsou, {Sheng Ying} and Mayumi Ueta and Simona Volpi and Chen Wan and Hongsheng Wang and Wang, {Zhao Qing} and Jessica Weintraub and Cindy Whale and Wheatley, {Lisa M.} and Sonia Whyte-Croasdaile and Williams, {Kristina B.} and Galen Wright and Yeung, {Sonia N.} and Li Zhou and Chung, {Wen Hung} and Phillips, {Elizabeth J.} and Carleton, {Bruce C.}",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

month = apr,

doi = "10.1016/j.jdermsci.2020.02.003",

language = "English",

volume = "98",

pages = "2--12",

journal = "Journal of Dermatological Science",

issn = "0923-1811",

number = "1",

}

Chang, WC, Abe, R, Anderson, P, Anderson, W, Ardern-Jones, MR, Beachkofsky, TM, Bellón, T, Biala, AK, Bouchard, C, Cavalleri, GL, Chapman, N, Chodosh, J, Choi, HK, Cibotti, RR, Divito, SJ, Dewar, K, Dehaeck, U, Etminan, M, Forbes, D, Fuchs, E, Goldman, JL, Holmes, JH, Hope, EA, Hung, SI, Hsieh, CL, Iovieno, A, Jagdeo, J, Kim, MK, Koelle, DM, Lacouture, ME, Le Pallec, S, Lehloenya, RJ, Lim, R, Lowe, A, McCawley, J, McCawley, J, Micheletti, RG, Mockenhaupt, M, Niemeyer, K, Norcross, MA, Oboh, D, Olteanu, C, Pasieka, HB, Peter, J, Pirmohamed, M, Rieder, M, Saeed, HN, Shear, NH, Shieh, C, Straus, S, Sukasem, C, Sung, C, Trubiano, JA, Tsou, SY, Ueta, M, Volpi, S, Wan, C, Wang, H, Wang, ZQ, Weintraub, J, Whale, C, Wheatley, LM, Whyte-Croasdaile, S, Williams, KB, Wright, G, Yeung, SN, Zhou, L, Chung, WH, Phillips, EJ & Carleton, BC 2020, 'SJS/TEN 2019: From science to translation', Journal of Dermatological Science, vol. 98, no. 1, pp. 2-12. https://doi.org/10.1016/j.jdermsci.2020.02.003

TY - JOUR

T1 - SJS/TEN 2019

T2 - From science to translation

AU - Chang, Wan Chun

AU - Abe, Riichiro

AU - Anderson, Paul

AU - Anderson, Wanpen

AU - Ardern-Jones, Michael R.

AU - Beachkofsky, Thomas M.

AU - Bellón, Teresa

AU - Biala, Agnieszka K.

AU - Bouchard, Charles

AU - Cavalleri, Gianpiero L.

AU - Chapman, Nicole

AU - Chodosh, James

AU - Choi, Hyon K.

AU - Cibotti, Ricardo R.

AU - Divito, Sherrie J.

AU - Dewar, Karen

AU - Dehaeck, Ulrike

AU - Etminan, Mahyar

AU - Forbes, Diane

AU - Fuchs, Esther

AU - Goldman, Jennifer L.

AU - Holmes, James H.

AU - Hope, Elyse A.

AU - Hung, Shuen Iu

AU - Hsieh, Chia Ling

AU - Iovieno, Alfonso

AU - Jagdeo, Julienne

AU - Kim, Mee Kum

AU - Koelle, David M.

AU - Lacouture, Mario E.

AU - Le Pallec, Sophie

AU - Lehloenya, Rannakoe J.

AU - Lim, Robyn

AU - Lowe, Angie

AU - McCawley, Jean

AU - McCawley, Julie

AU - Micheletti, Robert G.

AU - Mockenhaupt, Maja

AU - Niemeyer, Katie

AU - Norcross, Michael A.

AU - Oboh, Douglas

AU - Olteanu, Cristina

AU - Pasieka, Helena B.

AU - Peter, Jonathan

AU - Pirmohamed, Munir

AU - Rieder, Michael

AU - Saeed, Hajirah N.

AU - Shear, Neil H.

AU - Shieh, Christine

AU - Straus, Sabine

AU - Sukasem, Chonlaphat

AU - Sung, Cynthia

AU - Trubiano, Jason A.

AU - Tsou, Sheng Ying

AU - Ueta, Mayumi

AU - Volpi, Simona

AU - Wan, Chen

AU - Wang, Hongsheng

AU - Wang, Zhao Qing

AU - Weintraub, Jessica

AU - Whale, Cindy

AU - Wheatley, Lisa M.

AU - Whyte-Croasdaile, Sonia

AU - Williams, Kristina B.

AU - Wright, Galen

AU - Yeung, Sonia N.

AU - Zhou, Li

AU - Chung, Wen Hung

AU - Phillips, Elizabeth J.

AU - Carleton, Bruce C.

PY - 2020/4

Y1 - 2020/4

N2 - Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26–27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.

AB - Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26–27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs.

KW - Human leukocyte antigen (HLA)

KW - Pharmacogenomics

KW - Pharmacovigilance

KW - Severe cutaneous adverse reaction (SCAR)

KW - Stevens-Johnson syndrome (SJS)

KW - Toxic epidermal necrolysis (TEN)

UR - http://www.scopus.com/inward/record.url?scp=85081938408&partnerID=8YFLogxK

U2 - 10.1016/j.jdermsci.2020.02.003

DO - 10.1016/j.jdermsci.2020.02.003

M3 - Review article

C2 - 32192826

AN - SCOPUS:85081938408

SN - 0923-1811

VL - 98

SP - 2

EP - 12

JO - Journal of Dermatological Science

JF - Journal of Dermatological Science

IS - 1

ER -