Somatic Testing: Implications for Targeted Treatment

E. Kate Reed; Linda Steinmark; Diane C. Seibert; Emily Edelman

doi:10.1016/j.soncn.2018.12.009

Somatic Testing: Implications for Targeted Treatment

E. Kate Reed^*, Linda Steinmark, Diane C. Seibert, Emily Edelman

^*Corresponding author for this work

Graduate School of Nursing

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Objective: To provide an overview of key considerations for somatic testing for the purpose of targeting cancer treatment. Data Sources: Literature; research reports. Conclusion: Genomic testing of cancer cells to identify variants that drive the carcinogenic process is becoming common in clinical settings. Providers and patients need to weigh the potential benefits of testing with technologic and logistic issues. Implications for Nursing Practice: Testing is available for thousands of genomic variants to identify one or more to guide targeted treatment. Oncology nurses need to understand the benefits and limitations of participating in patient-centered implementation of this testing.

Original language	English
Pages (from-to)	22-33
Number of pages	12
Journal	Seminars in Oncology Nursing
Volume	35
Issue number	1
DOIs	https://doi.org/10.1016/j.soncn.2018.12.009
State	Published - Feb 2019

Keywords

genomic testing
precision medicine
somatic testing
targeted treatment

Access to Document

10.1016/j.soncn.2018.12.009

Cite this

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title = "Somatic Testing: Implications for Targeted Treatment",

abstract = "Objective: To provide an overview of key considerations for somatic testing for the purpose of targeting cancer treatment. Data Sources: Literature; research reports. Conclusion: Genomic testing of cancer cells to identify variants that drive the carcinogenic process is becoming common in clinical settings. Providers and patients need to weigh the potential benefits of testing with technologic and logistic issues. Implications for Nursing Practice: Testing is available for thousands of genomic variants to identify one or more to guide targeted treatment. Oncology nurses need to understand the benefits and limitations of participating in patient-centered implementation of this testing.",

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