Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults

Monique Bouvier; Wei Ju Chen; John C. Arnold; Mary P. Fairchok; Patrick J. Danaher; Tahaniyat Lalani; Leslie Malone; Deepika Mor; Michelande Ridoré; Timothy H. Burgess; Eugene V. Millar

doi:10.1111/irv.12538

Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults

Monique Bouvier
, Wei Ju Chen
, John C. Arnold
, Mary P. Fairchok
, Patrick J. Danaher
, Tahaniyat Lalani
, Leslie Malone
, Deepika Mor
, Michelande Ridoré
, Timothy H. Burgess
, Eugene V. Millar^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Human coronavirus (HCoV) is a known cause of influenza-like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR-positive for HCoV. The distribution of species was as follows: HCoV-OC43 (34%), HCoV-229E (28%), HCoV-NL63 (22%), and HCoV-HKU1 (16%). We did not observe species-specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV-HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness.

Original language	English
Pages (from-to)	299-303
Number of pages	5
Journal	Influenza and other Respiratory Viruses
Volume	12
Issue number	2
DOIs	https://doi.org/10.1111/irv.12538
State	Published - Mar 2018
Externally published	Yes

Keywords

clinical characteristics
coronavirus
influenza-like illness

Access to Document

10.1111/irv.12538

Cite this

Bouvier, M., Chen, W. J., Arnold, J. C., Fairchok, M. P., Danaher, P. J., Lalani, T., Malone, L., Mor, D., Ridoré, M., Burgess, T. H., & Millar, E. V. (2018). Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults. Influenza and other Respiratory Viruses, 12(2), 299-303. https://doi.org/10.1111/irv.12538

@article{f5f8d59d80604a9992ebf1d9cf04d98a,

title = "Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults",

abstract = "Human coronavirus (HCoV) is a known cause of influenza-like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12\% of subjects were PCR-positive for HCoV. The distribution of species was as follows: HCoV-OC43 (34\%), HCoV-229E (28\%), HCoV-NL63 (22\%), and HCoV-HKU1 (16\%). We did not observe species-specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV-HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness.",

keywords = "clinical characteristics, coronavirus, influenza-like illness",

author = "Monique Bouvier and Chen, \{Wei Ju\} and Arnold, \{John C.\} and Fairchok, \{Mary P.\} and Danaher, \{Patrick J.\} and Tahaniyat Lalani and Leslie Malone and Deepika Mor and Michelande Ridor{\'e} and Burgess, \{Timothy H.\} and Millar, \{Eugene V.\}",

note = "Publisher Copyright: {\textcopyright} 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley \& Sons Ltd.",

year = "2018",

month = mar,

doi = "10.1111/irv.12538",

language = "English",

volume = "12",

pages = "299--303",

journal = "Influenza and other Respiratory Viruses",

issn = "1750-2640",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "2",

}

TY - JOUR

T1 - Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults

AU - Bouvier, Monique

AU - Chen, Wei Ju

AU - Arnold, John C.

AU - Fairchok, Mary P.

AU - Danaher, Patrick J.

AU - Lalani, Tahaniyat

AU - Malone, Leslie

AU - Mor, Deepika

AU - Ridoré, Michelande

AU - Burgess, Timothy H.

AU - Millar, Eugene V.

PY - 2018/3

Y1 - 2018/3

N2 - Human coronavirus (HCoV) is a known cause of influenza-like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR-positive for HCoV. The distribution of species was as follows: HCoV-OC43 (34%), HCoV-229E (28%), HCoV-NL63 (22%), and HCoV-HKU1 (16%). We did not observe species-specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV-HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness.

AB - Human coronavirus (HCoV) is a known cause of influenza-like illness (ILI). In a multisite, observational, longitudinal study of ILI among otherwise healthy adolescents and adults, 12% of subjects were PCR-positive for HCoV. The distribution of species was as follows: HCoV-OC43 (34%), HCoV-229E (28%), HCoV-NL63 (22%), and HCoV-HKU1 (16%). We did not observe species-specific differences in the clinical characteristics of HCoV infection, with the exception of HCoV-HKU1, for which the severity of gastrointestinal symptoms trended higher on the fourth day of illness.

KW - clinical characteristics

KW - coronavirus

KW - influenza-like illness

UR - https://www.scopus.com/pages/publications/85041339676

U2 - 10.1111/irv.12538

DO - 10.1111/irv.12538

M3 - Article

C2 - 29350887

AN - SCOPUS:85041339676

SN - 1750-2640

VL - 12

SP - 299

EP - 303

JO - Influenza and other Respiratory Viruses

JF - Influenza and other Respiratory Viruses

IS - 2

ER -

Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults

Abstract

Keywords

Access to Document

Fingerprint

Cite this