Stability of certain coagulation factors and metabolic activities of platelets in stored blood

J. Worth Estes*, Joseph J. McGovern, Robert Goldstein, Mary Rota

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The stability of certain coagulation factors and metabolic activities of platelets separated from whole anticoagulated blood stored for 21 to 24 days was studied. Platelet factor I was found to decrease. Platelet factor II disappeared completely. Platelet factor III, measured by the recalcification time and thromboplastin generation test, did not decrease. Platelet factor IV did not decrease. The ability of platelets to promote clot retraction was lost after 21 days. Oxygen consumption and glucose utilization were found in both fresh and aged platelets.

Original languageEnglish
Pages (from-to)436-444
Number of pages9
JournalJournal of Laboratory and Clinical Medicine
Volume59
Issue number3
StatePublished - Mar 1962
Externally publishedYes

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