Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin

Robert G. Lerner, Robert Goldstein, Grace Cummings

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


Leukocytes incubated in vitro in plasma or serum, but not in saline, develop a potent procoagulant activity like tissue factor. This activity is not present in freshly collected leukocytes from normal individuals. The generation of activity is stimulated by gram-negative endotoxin.

Original languageEnglish
Pages (from-to)145-148
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number1
StatePublished - Oct 1971
Externally publishedYes


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