Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin

Robert G. Lerner; Robert Goldstein; Grace Cummings

doi:10.3181/00379727-138-35848

Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin

Robert G. Lerner, Robert Goldstein, Grace Cummings

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

Leukocytes incubated in vitro in plasma or serum, but not in saline, develop a potent procoagulant activity like tissue factor. This activity is not present in freshly collected leukocytes from normal individuals. The generation of activity is stimulated by gram-negative endotoxin.

Original language	English
Pages (from-to)	145-148
Number of pages	4
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	138
Issue number	1
DOIs	https://doi.org/10.3181/00379727-138-35848
State	Published - Oct 1971
Externally published	Yes

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@article{785655cb63934323b02221cfd7d6e803,

title = "Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin",

abstract = "Leukocytes incubated in vitro in plasma or serum, but not in saline, develop a potent procoagulant activity like tissue factor. This activity is not present in freshly collected leukocytes from normal individuals. The generation of activity is stimulated by gram-negative endotoxin.",

author = "Lerner, {Robert G.} and Robert Goldstein and Grace Cummings",

note = "Funding Information: Supported by NIH Grants AM 05423-08 and HE 06966.",

year = "1971",

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pages = "145--148",

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T1 - Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin

AU - Lerner, Robert G.

AU - Goldstein, Robert

AU - Cummings, Grace

N1 - Funding Information: Supported by NIH Grants AM 05423-08 and HE 06966.

PY - 1971/10

Y1 - 1971/10

N2 - Leukocytes incubated in vitro in plasma or serum, but not in saline, develop a potent procoagulant activity like tissue factor. This activity is not present in freshly collected leukocytes from normal individuals. The generation of activity is stimulated by gram-negative endotoxin.

AB - Leukocytes incubated in vitro in plasma or serum, but not in saline, develop a potent procoagulant activity like tissue factor. This activity is not present in freshly collected leukocytes from normal individuals. The generation of activity is stimulated by gram-negative endotoxin.

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U2 - 10.3181/00379727-138-35848

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M3 - Article

C2 - 4942184

AN - SCOPUS:0015135949

SN - 0037-9727

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EP - 148

JO - Proceedings of the Society for Experimental Biology and Medicine

JF - Proceedings of the Society for Experimental Biology and Medicine

IS - 1

ER -

Stimulation of Human Leukocyte Thromboplastic Activity by Endotoxin

Abstract

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