Surviving Sepsis After Burn Campaign

David G. Greenhalgh*, David M. Hill, David M. Burmeister, Eduardo I. Gus, Heather Cleland, Alex Padiglione, Dane Holden, Fredrik Huss, Michelle S. Chew, John C. Kubasiak, Aidan Burrell, William Manzanares, María Chacón Gómez, Yuya Yoshimura, Folke Sjöberg, Wei Guo Xie, Paula Egipto, Athina Lavrentieva, Arpana Jain, Ariel Miranda-AltamiranoEd Raby, Ignacio Aramendi, Soman Sen, Kevin K. Chung, Renata Jennifer Quintana Alvarez, Chunmao Han, Asako Matsushima, Moustafa Elmasry, Yan Liu, Carlos Segovia Donoso, Alberto Bolgiani, Laura S. Johnson, Luiz Philipe Molina Vana, Rosario Valdez Duval de Romero, Nikki Allorto, Gerald Abesamis, Virginia Nuñez Luna, Alfredo Gragnani, Carolina Bonilla González, Hugo Basilico, Fiona Wood, James Jeng, Andrew Li, Mervyn Singer, Gaoxing Luo, Tina Palmieri, Steven Kahn, Victor Joe, Robert Cartotto

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Introduction: The Surviving Sepsis Campaign was developed to improve outcomes for all patients with sepsis. Despite sepsis being the primary cause of death after thermal injury, burns have always been excluded from the Surviving Sepsis efforts. To improve sepsis outcomes in burn patients, an international group of burn experts developed the Surviving Sepsis After Burn Campaign (SSABC) as a testable guideline to improve burn sepsis outcomes. Methods: The International Society for Burn Injuries (ISBI) reached out to regional or national burn organizations to recommend members to participate in the program. Two members of the ISBI developed specific “patient/population, intervention, comparison and outcome” (PICO) questions that paralleled the 2021 Surviving Sepsis Campaign [1]. SSABC participants were asked to search the current literature and rate its quality for each topic. At the Congress of the ISBI, in Guadalajara, Mexico, August 28, 2022, a majority of the participants met to create “statements” based on the literature. The “summary statements” were then sent to all members for comment with the hope of developing an 80% consensus. After four reviews, a consensus statement for each topic was created or “no consensus” was reported. Results: The committee developed sixty statements within fourteen topics that provide guidance for the early treatment of sepsis in burn patients. These statements should be used to improve the care of sepsis in burn patients. The statements should not be considered as “static” comments but should rather be used as guidelines for future testing of the best treatments for sepsis in burn patients. They should be updated on a regular basis. Conclusion: Members of the burn community from the around the world have developed the Surviving Sepsis After Burn Campaign guidelines with the goal of improving the outcome of sepsis in burn patients.

Original languageEnglish
Pages (from-to)1487-1524
Number of pages38
Issue number7
StatePublished - Nov 2023
Externally publishedYes


  • Burns
  • Infection
  • Prevention
  • Resuscitation
  • Sepsis
  • Septic shock


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