Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: Implications for the 8-aminoquinoline class of anti-malarial compounds

Sean R. Marcsisin*, Jason C. Sousa, Gregory A. Reichard, Diana Caridha, Qiang Zeng, Norma Roncal, Ronan McNulty, Julio Careagabarja, Richard J. Sciotti, Jason W. Bennett, Victor E. Zottig, Gregory Deye, Qigui Li, Lisa Read, Mark Hickman, N. P.Dhammika Nanayakkara, Larry A. Walker, Bryan Smith, Victor Melendez, Brandon S. Pybus

*Corresponding author for this work

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