Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field

Nick J. Willett*, Michael L. Boninger, Laura J. Miller, Luis Alvarez, Tomoki Aoyama, Marzia Bedoni, Kelley Ann Brix, Carmelo Chisari, George Christ, Christopher L. Dearth, Trevor A. Dyson-Hudson, Christopher H. Evans, Stephen M. Goldman, Kenton Gregory, Alice Gualerzi, Joseph Hart, Akira Ito, Hiroshi Kuroki, M. Terry Loghmani, David L. MackGerard A. Malanga, Linda Noble-Haeusslein, Paul Pasquina, Joseph A. Roche, Lloyd Rose, Martin J. Stoddart, Junichi Tajino, Carmen Terzic, Kimberly S. Topp, William R. Wagner, Stuart J. Warden, Steven L. Wolf, Hua Xie, Thomas A. Rando, Fabrisia Ambrosio

*Corresponding author for this work

Research output: Contribution to journalComment/debate

25 Scopus citations


The growing field of regenerative rehabilitation has great potential to improve clinical outcomes for individuals with disabilities. However, the science to elucidate the specific biological underpinnings of regenerative rehabilitation–based approaches is still in its infancy and critical questions regarding clinical translation and implementation still exist. In a recent roundtable discussion from International Consortium for Regenerative Rehabilitation stakeholders, key challenges to progress in the field were identified. The goal of this article is to summarize those discussions and to initiate a broader discussion among clinicians and scientists across the fields of regenerative medicine and rehabilitation science to ultimately progress regenerative rehabilitation from an emerging field to an established interdisciplinary one. Strategies and case studies from consortium institutions—including interdisciplinary research centers, formalized courses, degree programs, international symposia, and collaborative grants—are presented. We propose that these strategic directions have the potential to engage and train clinical practitioners and basic scientists, transform clinical practice, and, ultimately, optimize patient outcomes.

Original languageEnglish
Pages (from-to)917-923
Number of pages7
JournalArchives of Physical Medicine and Rehabilitation
Issue number5
StatePublished - May 2020
Externally publishedYes


  • Regenerative medicine
  • Rehabilitation
  • Tissue engineering


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