Abstract
Microbial contamination in combat wounds can lead to opportunistic infections and adverse outcomes. However, current microbiological detection has a limited ability to capture microbial functional genes. This work describes the application of targeted metagenomic sequencing to profile wound bioburden and capture relevant wound-associated signatures for clinical utility. Ultimately, the ability to detect such signatures will help guide clinical decisions regarding wound care and management and aid in the prediction of wound outcomes.
Original language | English |
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Pages (from-to) | e0252023 |
Journal | Microbiology Spectrum |
Volume | 11 |
Issue number | 6 |
Early online date | 24 Oct 2023 |
DOIs | |
State | Published - 12 Dec 2023 |
Keywords
- Wound Infection/diagnosis
- Humans
- War-Related Injuries/diagnosis
- Metagenome