Thalidomide, an antiangiogenic agent with clinical activity in cancer

S. S.W. Ng, M. Brown, W. D. Figg

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations


Despite the teratogenic past of thalidomide, there is recent evidence indicating the drug's efficacy in the management of various diseases from immune disorders to cancers. The history, pharmacodynamic and pharmacokinetic properties of thalidomide in the clinic are discussed in this review article.

Original languageEnglish
Pages (from-to)194-199
Number of pages6
JournalBiomedicine and Pharmacotherapy
Issue number4
StatePublished - 2002
Externally publishedYes


  • HIV-infection
  • Thalidomide
  • VEGF
  • bFGF


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