TY - JOUR
T1 - The antimicrobial resistance monitoring and research (ARMoR) program
T2 - The US department of defense response to escalating antimicrobial resistance
AU - Lesho, Emil P.
AU - Waterman, Paige E.
AU - Chukwuma, Uzo
AU - McAuliffe, Kathryn
AU - Neumann, Charlotte
AU - Julius, Michael D.
AU - Crouch, Helen
AU - Chandrasekera, Ruvani
AU - English, Judith F.
AU - Clifford, Robert J.
AU - Kester, Kent E.
PY - 2014/8/1
Y1 - 2014/8/1
N2 - Responding to escalating antimicrobial resistance (AMR), the US Department of Defense implemented an enterprise-wide collaboration, the Antimicrobial Resistance Monitoring and Research Program, to aid in infection prevention and control. It consists of a network of epidemiologists, bioinformaticists, microbiology researchers, policy makers, hospital-based infection preventionists, and healthcare providers who collaborate to collect relevant AMR data, conduct centralized molecular characterization, and use AMR characterization feedback to implement appropriate infection prevention and control measures and influence policy. A particularly concerning type of AMR, carbapenem-resistant Enterobacteriaceae, significantly declined after the program was launched. Similarly, there have been no further reports or outbreaks of another concerning type of AMR, colistin resistance in Acinetobacter, in the Department of Defense since the program was initiated. However, bacteria containing AMR-encoding genes are increasing. To update program stakeholders and other healthcare systems facing such challenges, we describe the processes and impact of the program.
AB - Responding to escalating antimicrobial resistance (AMR), the US Department of Defense implemented an enterprise-wide collaboration, the Antimicrobial Resistance Monitoring and Research Program, to aid in infection prevention and control. It consists of a network of epidemiologists, bioinformaticists, microbiology researchers, policy makers, hospital-based infection preventionists, and healthcare providers who collaborate to collect relevant AMR data, conduct centralized molecular characterization, and use AMR characterization feedback to implement appropriate infection prevention and control measures and influence policy. A particularly concerning type of AMR, carbapenem-resistant Enterobacteriaceae, significantly declined after the program was launched. Similarly, there have been no further reports or outbreaks of another concerning type of AMR, colistin resistance in Acinetobacter, in the Department of Defense since the program was initiated. However, bacteria containing AMR-encoding genes are increasing. To update program stakeholders and other healthcare systems facing such challenges, we describe the processes and impact of the program.
KW - Antimicrobial resistance
KW - Department of Defense
KW - Infection prevention
KW - Surveillance
UR - http://www.scopus.com/inward/record.url?scp=84905025063&partnerID=8YFLogxK
U2 - 10.1093/cid/ciu319
DO - 10.1093/cid/ciu319
M3 - Review article
C2 - 24795331
AN - SCOPUS:84905025063
SN - 1058-4838
VL - 59
SP - 390
EP - 397
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 3
ER -