The association of percentage energy from fat and colon cancer risk among members of the US military

Stephanie Shao, Tzu Cheg Kao, Janet Eckhaus, Jolie Bourgeois, Kanchana Perera, Kangmin Zhu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Epidemiologic studies have previously reported an association between high fat intake and colon cancer risk. However, findings have generally been inconclusive. This study aimed to investigate the association between fat as a percentage of energy intake and colon cancer risk. Study subjects included 215 cases and 215 matched controls identified by the Defense Medical Surveillance System. Percentage energy from fat (Pfat) was estimated using a short dietary screener developed by the National Cancer Institute for two time periods: the year before the first blood draw and the year before colon cancer diagnosis. Conditional logistic regression analysis was used to assess the relationship between colon cancer risk and Pfat. Odds ratios and 95% confidence intervals (CIs) were calculated. Compared with the lowest quartile of Pfat, the adjusted odds of having colon cancer were 2.00 (95% CI 0.96-4.18), 2.83 (95% CI 1.41-5.66), and 3.37 (95% CI 1.58-7.17), respectively, for the second, third, and highest quartiles in the year before cancer diagnosis. Similar results were observed for Pfat at an earlier time point. Our findings suggest a positive association between Pfat and colon cancer in the US military population.

Original languageEnglish
Pages (from-to)188-194
Number of pages7
JournalEuropean Journal of Cancer Prevention
Issue number3
StatePublished - 4 Apr 2015
Externally publishedYes


  • colon cancer
  • dietary fat
  • epidemiology
  • percentage energy from fat


Dive into the research topics of 'The association of percentage energy from fat and colon cancer risk among members of the US military'. Together they form a unique fingerprint.

Cite this