The effects of ingested mammalian blood factors on vector arthropod immunity and physiology

Nazzy Pakpour*, Leyla Akman-Anderson, Yoram Vodovotz, Shirley Luckhart

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

31 Scopus citations

Abstract

The blood feeding behavior of disease-transmitting arthropods creates a unique intersection between vertebrate and invertebrate physiology. Here, we review host blood-derived factors that persist through blood digestion to affect the lifespan, reproduction, and immune responses of some of the most common arthropod vectors of human disease.

Original languageEnglish
Pages (from-to)243-254
Number of pages12
JournalMicrobes and Infection
Volume15
Issue number3
DOIs
StatePublished - Mar 2013
Externally publishedYes

Keywords

  • Insulin
  • Macrophage migration inhibitory factor (MIF)
  • Mosquito
  • Plasmodium
  • Tick
  • Transforming growth factor-beta (TGF-β)

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