The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer

Jieun Kang; Kathleen R. Jones; Sungil Jang; Cara H. Olsen; Yun Jung Yoo; D. Scott Merrell; Jeong Heon Cha

doi:10.1128/JCM.06293-11

The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer

Jieun Kang, Kathleen R. Jones, Sungil Jang, Cara H. Olsen, Yun Jung Yoo, D. Scott Merrell^*, Jeong Heon Cha

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

Original language	English
Pages (from-to)	1082-1085
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	50
Issue number	3
DOIs	https://doi.org/10.1128/JCM.06293-11
State	Published - Mar 2012
Externally published	Yes

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title = "The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer",

abstract = "We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.",

author = "Jieun Kang and Jones, {Kathleen R.} and Sungil Jang and Olsen, {Cara H.} and Yoo, {Yun Jung} and Merrell, {D. Scott} and Cha, {Jeong Heon}",

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AU - Kang, Jieun

AU - Jones, Kathleen R.

AU - Jang, Sungil

AU - Olsen, Cara H.

AU - Yoo, Yun Jung

AU - Merrell, D. Scott

AU - Cha, Jeong Heon

PY - 2012/3

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N2 - We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

AB - We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

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U2 - 10.1128/JCM.06293-11

DO - 10.1128/JCM.06293-11

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AN - SCOPUS:84857401649

SN - 0095-1137

VL - 50

SP - 1082

EP - 1085

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 3

ER -

The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer

Abstract

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