TY - JOUR
T1 - The global roadmap for advancing development of vaccines against sexually transmitted infections
T2 - Update and next steps
AU - Gottlieb, Sami L.
AU - Deal, Carolyn D.
AU - Giersing, Birgitte
AU - Rees, Helen
AU - Bolan, Gail
AU - Johnston, Christine
AU - Timms, Peter
AU - Gray-Owen, Scott D.
AU - Jerse, Ann E.
AU - Cameron, Caroline E.
AU - Moorthy, Vasee S.
AU - Kiarie, James
AU - Broutet, Nathalie
N1 - Publisher Copyright:
© 2016 World Health Organization.
PY - 2016/6/3
Y1 - 2016/6/3
N2 - In 2014, the World Health Organization, the US National Institutes of Health, and global technical partners published a comprehensive roadmap for development of new vaccines against sexually transmitted infections (STIs). Since its publication, progress has been made in several roadmap activities: obtaining better epidemiologic data to establish the public health rationale for STI vaccines, modeling the theoretical impact of future vaccines, advancing basic science research, defining preferred product characteristics for first-generation vaccines, and encouraging investment in STI vaccine development. This article reviews these overarching roadmap activities, provides updates on research and development of individual vaccines against herpes simplex virus, Chlamydia trachomatis, Neisseria gonorrhoeae, and Treponema pallidum, and discusses important next steps to advance the global roadmap for STI vaccine development.
AB - In 2014, the World Health Organization, the US National Institutes of Health, and global technical partners published a comprehensive roadmap for development of new vaccines against sexually transmitted infections (STIs). Since its publication, progress has been made in several roadmap activities: obtaining better epidemiologic data to establish the public health rationale for STI vaccines, modeling the theoretical impact of future vaccines, advancing basic science research, defining preferred product characteristics for first-generation vaccines, and encouraging investment in STI vaccine development. This article reviews these overarching roadmap activities, provides updates on research and development of individual vaccines against herpes simplex virus, Chlamydia trachomatis, Neisseria gonorrhoeae, and Treponema pallidum, and discusses important next steps to advance the global roadmap for STI vaccine development.
KW - Roadmap
KW - Sexually transmitted infections
KW - STI vaccine development
KW - Vaccines
UR - http://www.scopus.com/inward/record.url?scp=84965134111&partnerID=8YFLogxK
U2 - 10.1016/j.vaccine.2016.03.111
DO - 10.1016/j.vaccine.2016.03.111
M3 - Article
C2 - 27105564
AN - SCOPUS:84965134111
SN - 0264-410X
VL - 34
SP - 2939
EP - 2947
JO - Vaccine
JF - Vaccine
IS - 26
ER -