The Human Acellular Vessel (HAV) as a vascular conduit for infrainguinal arterial bypass

Armin Farazdaghi, Indrani Sen, Peter B. Anderson, Fahad Shuja, Todd E. Rasmussen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Autologous vein is the optimal conduit for peripheral arterial bypass surgery, a standard recently highlighted by findings from the BEST-CLI trial. The Human Acellular Vessel is a novel biologic conduit produced using regenerative medicine technologies with structural and mechanical properties like a human blood vessel. Not yet approved by the United States Food and Drug Administration, the Human Acellular Vessel is being studied as an alternative bypass conduit in patients with peripheral arterial disease, vascular injury, and those in need of arteriovenous access for hemodialysis. This report describes and illustrates the technical aspects of intraoperative handling specific to the use of this new and innovative technology.

Original languageEnglish
Article number101123
JournalJournal of Vascular Surgery Cases and Innovative Techniques
Volume9
Issue number3
DOIs
StatePublished - Sep 2023
Externally publishedYes

Keywords

  • Arterial reconstruction
  • Bioengineered vessel
  • Chronic limb-threatening ischemia
  • Critical limb-threatening ischemia
  • HAV
  • Human acellular vessel
  • Peripheral arterial disease
  • Regenerative medicine

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