The molecular epidemiology of herpes simplex viruses

B. Roizman, T. Buchman

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


For epidemiologic, and occasionally legal, reasons, it is sometimes necessary to know definitively which of the myriad strains of herpes simplex virus is responsible for a particular infection. A straightforward enzymatic method, using restriction endonucleases originally devised for viral DNA mapping, can unambiguously distinguish one strain from another even though the difference in their DNAs may be only a single base pair.

Original languageEnglish
Pages (from-to)95-104
Number of pages10
JournalHospital Practice
Issue number1
StatePublished - 1979
Externally publishedYes


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