The PediaFlow Pediatric Ventricular Assist Device

Peter D. Wearden, Victor O. Morell, Bradley B. Keller, Steven A. Webber, Harvey S. Borovetz*, Stephen F. Badylak, J. Robert Boston, Robert L. Kormos, Marina V. Kameneva, Marwan Simaan, Trevor A. Snyder, Hiro Tsukui, William R. Wagner, James F. Antaki, Chenguang Diao, Stijn Vandenberghe, Jeff Gardiner, Chung M. Li, Daniel Noh, Dave PadenBradley Paden, Jingchun Wu, Gill B. Bearnson, Gordon Jacobs, John Kirk, Pratap Khanwilkar, James W. Long, Scott Miles, John A. Hawkins, Peter C. Kouretas, R. E. Shaddy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


The very limited options available to treat ventricular failure in patients with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device (VAD). Our effort involves a consortium consisting of the University of Pittsburgh, Carnegie Mellon University, Children's Hospital of Pittsburgh, World Heart Corporation, and LaunchPoint Technologies, LLC. The overall aim of our program is to develop a highly reliable, biocompatible VAD for chronic support (6 months) of the unique and high-risk population of children between 3 kg and 15 kg (patients from birth to 2 years of age). The innovative pediatric VAD we are developing (PediaFlow™) is based on a miniature mixed-flow turbodynamic pump featuring magnetic levitation, with the design goal being to assure minimal blood trauma and risk of thrombosis. This article discusses the limitations of current pediatric cardiac assist treatment options and the work to date by our consortium toward the development of a pediatric VAD.

Original languageEnglish
Pages (from-to)92-98
Number of pages7
JournalPediatric Cardiac Surgery Annual
Issue number1
StatePublished - 2006
Externally publishedYes


  • Extracorporeal membrane oxygenation (ECMO)
  • Magnetic levitation
  • Turbodynamic pump
  • Ventricular assist device (VAD)


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