The relation of urinary cations to blood pressure in boys aged seven to eight years

Kangmin Zhu*, Shangpu He, Xiaoqin Pan, Xianrong Zheng, Yuan Gu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Zhu, KM (Oept of Epidemiology, Tongji Medical U., Wuhan, China), SP He, XQ Pan, XR Zheng, and Y Gu. The relation of urinary cations to blood pressure in boys aged seven to eight years. Am J Epidemiol 1987; 126:658-63.A study on the relation between urinary cations and blood pressure was conducted in Wuhan, China. A total of 148 boys aged 7-8 years entered the study from November 23, 1984, to January 13, 1985. Seven consecutive 24-hour urine specimens were collected and blood pressure was measured on the seven successive days corresponding to urine collection. The multiple regression showed that none of the sodium, potassium, calcium, and magnesium cations was statistically significantly related to blood pressure. However, the ratio of sodium/calcium or potassium/calcium in the urine was positively correlated with systolic pressure in multivariate analysis. The results suggest that there may be a complex interaction between sodium and calcium in their effects on blood pressure, and genetic background might have some influences on the sodium/calcium (or potassium/calcium)-blood pressure relation in the 7-8-year-old boys in the study.

Original languageEnglish
Pages (from-to)658-663
Number of pages6
JournalAmerican Journal of Epidemiology
Volume126
Issue number4
DOIs
StatePublished - Oct 1987

Keywords

  • Blood pressure
  • Cations
  • Child
  • Urine

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