@article{9dc2ab8ce23f425f838f642318183a51,
title = "The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity",
abstract = "Little is known about severe acute respiratory syndrome coronavirus 2 {"}vaccine-breakthrough{"}infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.",
keywords = "SARS-CoV-2, live virus, patient-reported outcomes, symptoms, vaccine breakthrough",
author = "Pollett, {Simon D.} and Richard, {Stephanie A.} and Fries, {Anthony C.} and Simons, {Mark P.} and Katrin Mende and Tahaniyat Lalani and Tida Lee and Sharon Chi and Rupal Mody and Cristian Madar and Anuradha Ganesan and Larson, {Derek T.} and Colombo, {Christopher J.} and Rhonda Colombo and Samuels, {Emily C.} and Broder, {Christopher C.} and Laing, {Eric D.} and Smith, {Darci R.} and David Tribble and Agan, {Brian K.} and Burgess, {Timothy H.}",
note = "Publisher Copyright: {\textcopyright} 2021 The Author(s).",
year = "2022",
month = mar,
day = "1",
doi = "10.1093/cid/ciab543",
language = "English",
volume = "74",
pages = "897--900",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "5",
}