Abstract
Mass spectrometry is used routinely for large-scale protein identification from complex biological mixtures. Recently, relative quantitation approach on the basis of spectra count has been applied in several cancer proteomic studies. In this review, we examine the mechanism of this technique and highlight several important parameters associated with its application.
| Original language | English |
|---|---|
| Pages (from-to) | 135-142 |
| Number of pages | 8 |
| Journal | Cancer Genomics and Proteomics |
| Volume | 9 |
| Issue number | 3 |
| State | Published - 2012 |
| Externally published | Yes |
Keywords
- Label-free quantitation
- Mass spectrometry
- Proteomics
- Review
- Spectra count