TY - JOUR
T1 - The Use of Tramadol for Acute Heroin Withdrawal
T2 - A Comparison to Clonidine
AU - Sobey, Paul W.
AU - Parran, Theodore V.
AU - Grey, Scott F.
AU - Adelman, Christopher L.
AU - Yu, Jaehak
N1 - Funding Information:
Funding support was provided by the Cuyahoga County Alcohol and Drug Addiction Services Board; the Department of Family Medicine at University Hospitals of Cleveland, Ohio; the Veteran Administration Special Fellowships in Substance Abuse and the Center for Substance Abuse Prevention.
PY - 2003
Y1 - 2003
N2 - Using a retrospective chart review, 59 patients detoxified with tramadol were compared to 85 patients detoxified with clonidine on rates of leaving against medical advice (AMA) and control of withdrawal symptoms. Patients detoxified with tramadol had 23% (95% CI, 0.09-0.59; P < .01) the risk of leaving AMA and scored an average of 0.24 points lower (95% CI, 0.08-0.41; P < .01) on a 0-3 point withdrawal symptom scale compared to patients detoxified with clonidine. This preliminary study indicates that tramadol is more effective in managing withdrawal than clonidine, and may be especially useful in outpatient detoxification.
AB - Using a retrospective chart review, 59 patients detoxified with tramadol were compared to 85 patients detoxified with clonidine on rates of leaving against medical advice (AMA) and control of withdrawal symptoms. Patients detoxified with tramadol had 23% (95% CI, 0.09-0.59; P < .01) the risk of leaving AMA and scored an average of 0.24 points lower (95% CI, 0.08-0.41; P < .01) on a 0-3 point withdrawal symptom scale compared to patients detoxified with clonidine. This preliminary study indicates that tramadol is more effective in managing withdrawal than clonidine, and may be especially useful in outpatient detoxification.
KW - Clonidine therapeutic use
KW - Cohort studies
KW - Drug
KW - Heroin dependence drug therapy
KW - Medical detoxification
KW - Tramadol therapeutic use
UR - http://www.scopus.com/inward/record.url?scp=0842266609&partnerID=8YFLogxK
U2 - 10.1300/J069v22n04_03
DO - 10.1300/J069v22n04_03
M3 - Article
C2 - 14723475
AN - SCOPUS:0842266609
SN - 1055-0887
VL - 22
SP - 13
EP - 25
JO - Journal of Addictive Diseases
JF - Journal of Addictive Diseases
IS - 4
ER -