Therapeutic antioxidant medical gas

Atsunori Nakao*, Ryujiro Sugimoto, Timothy R. Billiar, Kenneth R. McCurry

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

110 Scopus citations


Medical gases are pharmaceutical gaseous molecules which offer solutions to medical needs and include traditional gases, such as oxygen and nitrous oxide, as well as gases with recently discovered roles as biological messenger molecules, such as carbon monoxide, nitric oxide and hydrogen sulphide. Medical gas therapy is a relatively unexplored field of medicine; however, a recent increasing in the number of publications on medical gas therapies clearly indicate that there are significant opportunities for use of gases as therapeutic tools for a variety of disease conditions. In this article, we review the recent advances in research on medical gases with antioxidant properties and discuss their clinical applications and therapeutic properties.

Original languageEnglish
Pages (from-to)1-13
Number of pages13
JournalJournal of Clinical Biochemistry and Nutrition
Issue number1
StatePublished - Jan 2009
Externally publishedYes


  • Antioxidant
  • Carbon monoxide
  • Hydrogen
  • Medical gas
  • Nitric oxide


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