Tissue potassium in chronic dialysis patients

D. E. Butkus, A. C. Alfrey, N. L. Miller

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Postmortem tissue analysis revealed significant potassium deficits in 58% of 27 patients maintained on chronic hemodialysis for periods of 2-75 mth against dialysates containing 0-2.6 mEq/l of potassium. Potassium depletion was observed with all dialysate potassium concentrations but was greatest in patients dialyzed against potassium free baths. The potassium deficit occurred primarily in skeletal muscle, myocardium, and brain. Myocardial potassium concentration was severely reduced in the majority of patients maintained on potassium free dialysates and also correlated closely with muscle potassium concentration.

Original languageEnglish
Pages (from-to)314-324
Number of pages11
Issue number4
StatePublished - 1974
Externally publishedYes


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