Tracking the re-emergence of epidemic chikungunya virus in Indonesia

Kanti Laras, Nono C. Sukri, Ria P. Larasati, Michael J. Bangs, Rizal Kosim, A. Djauzi, Tony Wandra, John Master, Herman Kosasih, Sri Hartati, Charmagne Beckett, Endang R. Sedyaningsih, H. James Beecham, Andrew L. Corwin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

213 Scopus citations

Abstract

Twenty-four distinct outbreaks of probable chikungunya (CHIK) etiology were identified throughout Indonesia from September 2001 to March 2003, after a near 20-year hiatus of epidemic CHIK activity in the country. Thirteen outbreak reports were based on clinical observations alone, and 11 confirmed by serological/virological methods. Detailed epidemiological profiles of two investigated outbreaks in Bogor and Bekasi are presented. Human sera were screened using an ELISA for IgM and IgG anti-CHIK antibodies. Additionally, reverse transcriptase PCR and virus isolation were attempted for virus identification. The mean age of cases was 37 ± 18 years in Bogor and 33 ± 20 years in Bekasi. There was no outstanding case-clustering, although outbreak-affected households were observed to be geographically grouped within villages. The attack rates in Bogor and Bekasi were 2.8/1000 and 6.7/1000 inhabitants respectively. Both outbreaks started in the rainy season following increased Aedes aegypti and A. albopictus densities.

Original languageEnglish
Pages (from-to)128-141
Number of pages14
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume99
Issue number2
DOIs
StatePublished - Feb 2005
Externally publishedYes

Keywords

  • Chikungunya virus
  • Epidemic
  • Indonesia

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