Translational research in composite tissue allotransplantation

Linda C. Cendales, David E. Kleiner, Allan D. Kirk

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Patients suffering from severe tissue loss secondary to burns, traumatic injuries, or tumor resections have limited options for reconstruction when autologous tissue for reconstruction is scarce. Composite tissue allotransplantation (CTA) has recently been introduced as a potential clinical treatment for functionally significant tissue loss. CTA has emerged as an amalgamation of advanced microsurgical techniques for limb and flap autotransplantation, and improved immunosuppressive agents to prevent rejection. However, as a developing field, it is yet to have its unique immunological properties established.

Original languageEnglish
Title of host publicationTransplantation of Composite Tissue Allografts
PublisherSpringer US
Number of pages12
ISBN (Electronic)9780387746821
ISBN (Print)9780387746814
StatePublished - 2008
Externally publishedYes


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