Travel, Diarrhea, Antibiotics, Antimicrobial Resistance and Practice Guidelines—a Holistic Approach to a Health Conundrum

Purpose of Review: Given the recent interest in the interface between travelers’ diarrhea (TD) management guidelines and antimicrobial resistance from both the patient and population perspectives, we have undertaken a review of the evidence with an aim towards practical and pragmatic recommendations. Recent Findings: Antimicrobial resistance continues to be an existential threat. Therefore, an update is needed on the pathogens that cause TD, the role of antibiotics, the potential changes in microbiome and acquisiton of multi-drug resistant (MDR) bacteria, and lastly the impact of MDR acquisition of the traveler on individual, community, and global health through a holistic framework. Summary: Important research gaps and opportunities in this area are identified, as well as practical guidance for the travel medicine community offered.