TY - JOUR
T1 - Treatment Failure After Repair of Displaced Femoral Neck Fractures in Patients Compared by "Decade of Life"
T2 - An Analysis of 565 Cases in Adults Less Than 60 years of Age
AU - Collinge, Cory A.
AU - Giga, Kashmeera
AU - Roser, Thomas
AU - Lebus, George F.
AU - Beltran, Michael J.
AU - Crist, Brett
AU - Sems, Stephen A.
AU - Gardner, Michael J.
AU - Sagi, H. Claude
AU - Archdeacon, Michael T.
AU - Mir, Hassan R.
AU - Rodriguez-Buitrago, Andres
AU - Mitchell, Phillip
AU - Tornetta, Paul
AU - Cannada, Lisa K.
AU - Streufert, Ben
AU - Robinette, Patton
AU - O'Neill, David
AU - Olszewski, Nathan
AU - Rainer, William
AU - Yuan, Brandon
AU - Jeray, Kyle
AU - Cardin Poza, Stefano
AU - Tanner, Stephanie
AU - Avilucea, Frank
AU - Schumaier, Adam
AU - Ketz, John
AU - Hedgecock, Jon
AU - Coles, Chad
AU - Trask, Kelly
AU - Macdonald, Shelley
AU - Scolaro, John
AU - Bustillo, David
AU - Horner, Kevin
AU - Bergin, Patrick
AU - Miles, Daniel T.
AU - Spitler, Clay
AU - Ahn, Jaimo
AU - Bram, Joshua T.
AU - Morris, Tyler
AU - Hsu, Joseph
AU - Buck, J. Stewart
AU - Schmidt, Andrew
AU - Westberg, J. R.
AU - Tejwani, Nirmal
AU - Mehta, Devan
AU - Virkus, Walter
AU - Harrington, Justin
AU - Weber, Timothy
AU - Flint, Kathy
AU - Mullis, Brian
AU - Lancaster, Alex
AU - Liporace, Frank
AU - Adams, Don
AU - Horwitz, Daniel
AU - Yaacobi, Eyal
AU - Hymes, Robert
AU - Kilcoyne, Kelly
AU - Lusk, Dominic
N1 - Publisher Copyright:
Copyright © 2024 Wolters Kluwer Health, Inc.
PY - 2024/8/1
Y1 - 2024/8/1
N2 - OBJECTIVES:To study the results of displaced femoral neck fractures (FNFs) in adults less than 60 years of age by comparing patients, injury, treatment, and the characteristics of treatment failure specifically according to patients' age at injury, that is, by their "decade of life"[ie, "under 30"(29 years and younger), "the 30s"(30-39 years), "the 40s"(40-49 years), and "the 50s"(50-59 years)].METHODS:Design:Multicenter retrospective comparative cohort series.Setting:Twenty-six North American Level 1 Trauma Centers.Patient Selection Criteria:Skeletally mature patients aged 18-59 years with operative repair of displaced FNFs.Outcome Measures and Comparisons:Main outcome measures were treatment failures (fixation failure and/or nonunion, osteonecrosis, malunion, and the need for subsequent major reconstructive surgery (arthroplasty or proximal femoral osteotomy). These were compared across decades of adult life through middle age (<30 years, 30-39 years, 40-49 years, and 50-59 years).RESULTS:Overall, treatment failure was observed in 264 of 565 (47%) of all hips. The mean age was 42.2 years, 35.8% of patients were women, and the mean Pauwels angle was 53.8 degrees. Complications and the need for major secondary surgeries increased with each increasing decade of life assessed: 36% of failure occurred in patients <30 years of age, 40% in their 30s, 48% in their 40s, and 57% in their 50s (P < 0.001). Rates of osteonecrosis increased with decades of life (under 30s and 30s vs. 40s vs. 50s developed osteonecrosis in 10%, 10%, 20%, and 27% of hips, P < 0.001), while fixation failure and/or nonunion only increased by decade of life to a level of trend (P = 0.06). Reparative methods varied widely between decade-long age groups, including reduction type (open vs. closed, P < 0.001), reduction quality (P = 0.030), and construct type (cannulated screws vs. fixed angle devices, P = 0.024), while some variables evaluated did not change with age group.CONCLUSIONS:Displaced FNFs in young and middle-aged adults are a challenging clinical problem with a high rate of treatment failure. Major complications and the need for complex reconstructive surgery increased greatly by decade of life with the patients in their sixth decade experiencing osteonecrosis at the highest rate seen among patients in the decades studied. Interestingly, treatments provided to patients in their 50s were notably different than those provided to younger patient groups.LEVEL OF EVIDENCE:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
AB - OBJECTIVES:To study the results of displaced femoral neck fractures (FNFs) in adults less than 60 years of age by comparing patients, injury, treatment, and the characteristics of treatment failure specifically according to patients' age at injury, that is, by their "decade of life"[ie, "under 30"(29 years and younger), "the 30s"(30-39 years), "the 40s"(40-49 years), and "the 50s"(50-59 years)].METHODS:Design:Multicenter retrospective comparative cohort series.Setting:Twenty-six North American Level 1 Trauma Centers.Patient Selection Criteria:Skeletally mature patients aged 18-59 years with operative repair of displaced FNFs.Outcome Measures and Comparisons:Main outcome measures were treatment failures (fixation failure and/or nonunion, osteonecrosis, malunion, and the need for subsequent major reconstructive surgery (arthroplasty or proximal femoral osteotomy). These were compared across decades of adult life through middle age (<30 years, 30-39 years, 40-49 years, and 50-59 years).RESULTS:Overall, treatment failure was observed in 264 of 565 (47%) of all hips. The mean age was 42.2 years, 35.8% of patients were women, and the mean Pauwels angle was 53.8 degrees. Complications and the need for major secondary surgeries increased with each increasing decade of life assessed: 36% of failure occurred in patients <30 years of age, 40% in their 30s, 48% in their 40s, and 57% in their 50s (P < 0.001). Rates of osteonecrosis increased with decades of life (under 30s and 30s vs. 40s vs. 50s developed osteonecrosis in 10%, 10%, 20%, and 27% of hips, P < 0.001), while fixation failure and/or nonunion only increased by decade of life to a level of trend (P = 0.06). Reparative methods varied widely between decade-long age groups, including reduction type (open vs. closed, P < 0.001), reduction quality (P = 0.030), and construct type (cannulated screws vs. fixed angle devices, P = 0.024), while some variables evaluated did not change with age group.CONCLUSIONS:Displaced FNFs in young and middle-aged adults are a challenging clinical problem with a high rate of treatment failure. Major complications and the need for complex reconstructive surgery increased greatly by decade of life with the patients in their sixth decade experiencing osteonecrosis at the highest rate seen among patients in the decades studied. Interestingly, treatments provided to patients in their 50s were notably different than those provided to younger patient groups.LEVEL OF EVIDENCE:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
KW - age
KW - decade
KW - failure
KW - femoral neck fracture
KW - young
UR - http://www.scopus.com/inward/record.url?scp=85199015667&partnerID=8YFLogxK
U2 - 10.1097/BOT.0000000000002840
DO - 10.1097/BOT.0000000000002840
M3 - Article
C2 - 39007657
AN - SCOPUS:85199015667
SN - 0890-5339
VL - 38
SP - 418
EP - 425
JO - Journal of Orthopaedic Trauma
JF - Journal of Orthopaedic Trauma
IS - 8
ER -