Tricyclic antidepressants for the prevention of migraine and tension-type headache

Jeffrey L. Jackson*, Elizabeth P. Berbano, Kent J. Dezee, Margretta M. Diemer, Jeffrey A. Mikita, Patrick G. O'Malley, Laura L. Sessums, William T. Shimeall

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


This is the protocol for a review and there is no abstract. The objectives are as follows: The objectives of the proposed review are to provide a comprehensive review and analysis of published reports of randomized controlled trials (RCTs) of tricyclic antidepressants for reducing headache burden among adults with migraine or tension-type headache (frequent episodic or chronic), and to determine whether efficacy varies according to the specific headache diagnosis or potentially important patient characteristics, such as coexisting depression.

Original languageEnglish
Article numberCD005036
JournalCochrane Database of Systematic Reviews
Issue number3
StatePublished - 28 Mar 2013
Externally publishedYes


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