Trimethoprim/sulfamethoxazole induced multiorgan dysfunction

Joshua Seung Oh Lee*, David Owshalimpur, Christina Schofield

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.

Original languageEnglish
Article number1454
JournalBMJ Case Reports
StatePublished - 2012
Externally publishedYes


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