Trimethoprim/sulfamethoxazole induced multiorgan dysfunction

Joshua Seung Oh Lee; David Owshalimpur; Christina Schofield

doi:10.1136/bcr-2012-007460

Trimethoprim/sulfamethoxazole induced multiorgan dysfunction

Joshua Seung Oh Lee^*, David Owshalimpur, Christina Schofield

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.

Original language	English
Article number	1454
Journal	BMJ Case Reports
DOIs	https://doi.org/10.1136/bcr-2012-007460
State	Published - 2012
Externally published	Yes

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title = "Trimethoprim/sulfamethoxazole induced multiorgan dysfunction",

abstract = "A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.",

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N2 - A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.

AB - A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.

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DO - 10.1136/bcr-2012-007460

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AN - SCOPUS:84872702323

SN - 1757-790X

JO - BMJ Case Reports

JF - BMJ Case Reports

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Trimethoprim/sulfamethoxazole induced multiorgan dysfunction

Abstract

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