Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

S. Pollett; M. C. Melendrez; I. Maljkovic Berry; S. Duchêne; H. Salje; D. A.T. Cummings; R. G. Jarman

doi:10.1016/j.meegid.2018.04.032

Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

S. Pollett^*, M. C. Melendrez, I. Maljkovic Berry, S. Duchêne, H. Salje, D. A.T. Cummings, R. G. Jarman

^*Corresponding author for this work

Infectious Disease Clinical Research Program (IDCRP)

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

Abstract

Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.

Original language	English
Pages (from-to)	279-295
Number of pages	17
Journal	Infection, Genetics and Evolution
Volume	62
DOIs	https://doi.org/10.1016/j.meegid.2018.04.032
State	Published - Aug 2018

Keywords

Dengue virus
Evolution
Molecular epidemiology
Phylogenetics

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10.1016/j.meegid.2018.04.032

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title = "Understanding dengue virus evolution to support epidemic surveillance and counter-measure development",

abstract = "Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.",

keywords = "Dengue virus, Evolution, Molecular epidemiology, Phylogenetics",

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doi = "10.1016/j.meegid.2018.04.032",

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TY - JOUR

T1 - Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

AU - Pollett, S.

AU - Melendrez, M. C.

AU - Maljkovic Berry, I.

AU - Duchêne, S.

AU - Salje, H.

AU - Cummings, D. A.T.

AU - Jarman, R. G.

PY - 2018/8

Y1 - 2018/8

N2 - Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.

AB - Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globalization, travel, climate change, urbanization, and expansion of the geographic range of the Ae.aegypti and Ae.albopictus vectors. Understanding DENV evolution offers valuable opportunities to enhance surveillance and response to DENV epidemics via advances in RNA virus sequencing, bioinformatics, phylogenetic and other computational biology methods. Here we provide a scoping overview of the evolution and molecular epidemiology of DENV and the range of ways that evolutionary analyses can be applied as a public health tool against this arboviral pathogen.

KW - Dengue virus

KW - Evolution

KW - Molecular epidemiology

KW - Phylogenetics

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U2 - 10.1016/j.meegid.2018.04.032

DO - 10.1016/j.meegid.2018.04.032

M3 - Review article

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AN - SCOPUS:85047434832

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VL - 62

SP - 279

EP - 295

JO - Infection, Genetics and Evolution

JF - Infection, Genetics and Evolution

ER -

Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

Abstract

Keywords

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