Upregulation of the androgen receptor during prostate cancer progression

Arun Singh, William D. Figg*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


The androgen receptor is one of the central factors in mediating prostate cancer progression and is an important target for treatment. Several possible mechanisms have been put forth as to how it promotes this process. In the January 2004 issue of Nature Medicine, Chen et al. report that the androgen receptor is consistently upregulated as hormone sensitive prostate cancer changes to a hormone refractory state. They also show that this change is intricately involved during the development of resistance to androgen ablation therapy.

Original languageEnglish
Pages (from-to)284-285
Number of pages2
JournalCancer Biology and Therapy
Issue number3
StatePublished - Mar 2004
Externally publishedYes


  • Androgen receptor
  • Cancer
  • Microarray
  • Prostate
  • Resistance


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