Use of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 to assess the performance of viral RNA quantitation tests

Linda L. Jagodzinski*, Debra L. Wiggins, Joshua L. McManis, Sandra Emery, Julie Overbaugh, Merlin Robb, Sharon Bodrug, Nelson L. Michael

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

Optimal management of human immunodeficiency virus type 1 (HIV-1) disease requires accurate quantitation of viral RNA concentrations in plasma. Evidence for increasing geographic intermixing of HIV-1 subtypes makes equivalent quantitation of all subtypes essential. The performances of six quantitative viral RNA tests are described, for the first time, with calibrated viral isolates of diverse subtypes.

Original languageEnglish
Pages (from-to)1247-1249
Number of pages3
JournalJournal of Clinical Microbiology
Volume38
Issue number3
DOIs
StatePublished - Mar 2000
Externally publishedYes

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