TY - JOUR
T1 - Use of Percutaneous Coronary Intervention Among Black and White Patients With End-Stage Renal Disease in the United States
AU - Nee, Robert
AU - Yan, Guofen
AU - Yuan, Christina M.
AU - Agodoa, Lawrence Y.
AU - Norris, Keith C.
N1 - Funding Information:
This research did not receive any funding from agencies in the public, commercial, or not‐for‐profit sectors. Dr Yan is supported in part by National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases grant 1R01DK112008‐01A1. Dr Norris is supported by NIH grants UL1TR000124 and P30AG021684.
Funding Information:
We identified Medicare primary patients aged >18 years who initiated on maintenance dialysis from January 1, 2009, through June 1, 2013, and were followed until December 31, 2013, from the 50 US states, the District of Columbia, and Puerto Rico. From this larger cohort, we identified 268 575 patients who were hospitalized and thus had documented Medicare claims through the The authors declare that all supporting data are available within the article. We conducted a retrospective cohort study using the USRDS, which incorporates baseline and follow‐up demographic and clinical data on nearly all patients accessing the Medicare ESRD program in the United States. International Classification of Diseases, Ninth Revision, Clinical Modification ( S1 We used the following S2 ICD‐9‐CM ) and Current Procedural Terminology codes. We used the following procedural codes for PCI: 00.66, 36.01, 36.02, 36.05, 36.06, 36.07, and 36.09 (Table ). Codes 36.01–36.05 resulted in no cases because these codes were deleted from the Centers for Medicare and Medicaid Services (CMS) procedure list in 2005. ICD‐9 codes for acute myocardial infarction (410.xx) and coronary atherosclerosis (414.00, 414.01, 414.0, 414.8) as primary discharge diagnoses (Table ). We merged the USRDS data set with the 2010 US Census to obtain zip code–level median household income (MHI) data. The primary outcome was time to receipt of PCI among dialysis‐dependent patients. This study was approved as exempt from review by the Walter Reed National Military Medical Center institutional review board.
Funding Information:
The views expressed in this paper are those of the authors and do not reflect the official policy of the National Institutes of Health, the Department of Army/Navy/Air Force, Department of Defense, or US government.
Publisher Copyright:
© 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.
PY - 2019/8/6
Y1 - 2019/8/6
N2 - Background: Racial disparities in invasive cardiac procedures such as percutaneous coronary intervention (PCI) in the general population are well documented; however, national-level data on such disparities in the end-stage renal disease (ESRD) population are lacking. We assessed racial differences in PCI between black and white patients with ESRD on maintenance dialysis. Methods and Results: Using the US Renal Data System database, we abstracted Medicare inpatient procedure claims for PCI in a cohort of 268 575 Medicare-primary patients who initiated treatment on maintenance dialysis from January 1, 2009, through June 1, 2013. We conducted Cox regression analyses with PCI being the event, adjusted for demographic characteristics, Hispanic ethnicity, cause of ESRD, comorbidities, and socioeconomic factors. We also assessed the probability of PCI, accounting for death or transplant in competing risk regression models. The crude incidence rate of PCI among white patients was 25.8 per 1000 patient-years versus 15.5 per 1000 patient-years among black patients. Cox regression analyses demonstrated that black patients were significantly less likely to undergo PCI compared with white patients (adjusted hazard ratio: 0.64; 95% CI, 0.62–0.67; P<0.001). In the competing risk models, the racial gap for PCI among black and white patients remained significant with death (subdistribution hazard ratio: 0.81; 95% CI, 0.76–0.85; P<0.001) or transplant as a competing event (subdistribution hazard ratio: 0.67; 95% CI, 0.64–0.70; P<0.001). Conclusions: A racial gap exists in PCI use among dialysis patients despite having comprehensive coverage with Medicare. These findings persisted despite accounting for demographic, clinical, socioeconomic factors, and death or transplant as competing events.
AB - Background: Racial disparities in invasive cardiac procedures such as percutaneous coronary intervention (PCI) in the general population are well documented; however, national-level data on such disparities in the end-stage renal disease (ESRD) population are lacking. We assessed racial differences in PCI between black and white patients with ESRD on maintenance dialysis. Methods and Results: Using the US Renal Data System database, we abstracted Medicare inpatient procedure claims for PCI in a cohort of 268 575 Medicare-primary patients who initiated treatment on maintenance dialysis from January 1, 2009, through June 1, 2013. We conducted Cox regression analyses with PCI being the event, adjusted for demographic characteristics, Hispanic ethnicity, cause of ESRD, comorbidities, and socioeconomic factors. We also assessed the probability of PCI, accounting for death or transplant in competing risk regression models. The crude incidence rate of PCI among white patients was 25.8 per 1000 patient-years versus 15.5 per 1000 patient-years among black patients. Cox regression analyses demonstrated that black patients were significantly less likely to undergo PCI compared with white patients (adjusted hazard ratio: 0.64; 95% CI, 0.62–0.67; P<0.001). In the competing risk models, the racial gap for PCI among black and white patients remained significant with death (subdistribution hazard ratio: 0.81; 95% CI, 0.76–0.85; P<0.001) or transplant as a competing event (subdistribution hazard ratio: 0.67; 95% CI, 0.64–0.70; P<0.001). Conclusions: A racial gap exists in PCI use among dialysis patients despite having comprehensive coverage with Medicare. These findings persisted despite accounting for demographic, clinical, socioeconomic factors, and death or transplant as competing events.
KW - angioplasty and stenting
KW - end-stage renal disease
KW - percutaneous coronary intervention
KW - race and ethnicity
UR - http://www.scopus.com/inward/record.url?scp=85075006380&partnerID=8YFLogxK
U2 - 10.1161/JAHA.119.012101
DO - 10.1161/JAHA.119.012101
M3 - Article
C2 - 31331221
AN - SCOPUS:85075006380
SN - 2047-9980
VL - 8
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 15
M1 - e012101
ER -