Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory

Ginamarie Foglia; G. Donald Royster IV; K. Monique Wasunna; Rukia Kibaya; Jennifer A. Malia; Eva K. Calero; Warren Sateren; Philip O. Renzullo; Merlin L. Robb; Deborah L. Birx; Nelson L. Michael

doi:10.1128/JCM.42.8.3850-3852.2004

Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory

Ginamarie Foglia, G. Donald Royster IV, K. Monique Wasunna, Rukia Kibaya, Jennifer A. Malia, Eva K. Calero, Warren Sateren, Philip O. Renzullo, Merlin L. Robb, Deborah L. Birx, Nelson L. Michael^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We report a prospective comparison of human immunodeficiency virus type 1 testing by enzyme immunoassay and Western blot with four rapid tests of 486 subjects performed in rural Kenya. Rapid test sensitivity was 100%. Specificity ranged from 99.1 to 100%. Combined use of two Food and Drug Administration- approved rapid tests yielded a single false-positive result.

Original language	English
Pages (from-to)	3850-3852
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	42
Issue number	8
DOIs	https://doi.org/10.1128/JCM.42.8.3850-3852.2004
State	Published - Aug 2004
Externally published	Yes

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Foglia, G., Royster IV, G. D., Wasunna, K. M., Kibaya, R., Malia, J. A., Calero, E. K., Sateren, W., Renzullo, P. O., Robb, M. L., Birx, D. L., & Michael, N. L. (2004). Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory. Journal of Clinical Microbiology, 42(8), 3850-3852. https://doi.org/10.1128/JCM.42.8.3850-3852.2004

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abstract = "We report a prospective comparison of human immunodeficiency virus type 1 testing by enzyme immunoassay and Western blot with four rapid tests of 486 subjects performed in rural Kenya. Rapid test sensitivity was 100%. Specificity ranged from 99.1 to 100%. Combined use of two Food and Drug Administration- approved rapid tests yielded a single false-positive result.",

author = "Ginamarie Foglia and {Royster IV}, {G. Donald} and Wasunna, {K. Monique} and Rukia Kibaya and Malia, {Jennifer A.} and Calero, {Eva K.} and Warren Sateren and Renzullo, {Philip O.} and Robb, {Merlin L.} and Birx, {Deborah L.} and Michael, {Nelson L.}",

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Foglia, G, Royster IV, GD, Wasunna, KM, Kibaya, R, Malia, JA, Calero, EK, Sateren, W, Renzullo, PO, Robb, ML, Birx, DL & Michael, NL 2004, 'Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory', Journal of Clinical Microbiology, vol. 42, no. 8, pp. 3850-3852. https://doi.org/10.1128/JCM.42.8.3850-3852.2004

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AU - Foglia, Ginamarie

AU - Royster IV, G. Donald

AU - Wasunna, K. Monique

AU - Kibaya, Rukia

AU - Malia, Jennifer A.

AU - Calero, Eva K.

AU - Sateren, Warren

AU - Renzullo, Philip O.

AU - Robb, Merlin L.

AU - Birx, Deborah L.

AU - Michael, Nelson L.

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AB - We report a prospective comparison of human immunodeficiency virus type 1 testing by enzyme immunoassay and Western blot with four rapid tests of 486 subjects performed in rural Kenya. Rapid test sensitivity was 100%. Specificity ranged from 99.1 to 100%. Combined use of two Food and Drug Administration- approved rapid tests yielded a single false-positive result.

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Use of rapid and conventional testing technologies for human immunodeficiency virus type 1 serologic screening in a rural Kenyan reference laboratory

Abstract

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