Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

Darrell E. Singer; Noah Kiwanuka; David Serwadda; Fred Nalugoda; Linda Hird; Jamie Bulken-Hoover; Godfrey Kigozi; Jennifer A. Malia; Eva K. Calero; Warren Sateren; Merlin L. Robb; Fred Wabwire-Mangen; Maria Wawer; Ronald H. Gray; Nelson Sewankambo; Deborah L. Birx; Nelson L. Michael

doi:10.1128/JCM.43.10.5312-5315.2005

Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

Darrell E. Singer
, Noah Kiwanuka
, David Serwadda
, Fred Nalugoda
, Linda Hird
, Jamie Bulken-Hoover
, Godfrey Kigozi
, Jennifer A. Malia
, Eva K. Calero
, Warren Sateren
, Merlin L. Robb
, Fred Wabwire-Mangen
, Maria Wawer
, Ronald H. Gray
, Nelson Sewankambo
, Deborah L. Birx
, Nelson L. Michael^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

Original language	English
Pages (from-to)	5312-5315
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	43
Issue number	10
DOIs	https://doi.org/10.1128/JCM.43.10.5312-5315.2005
State	Published - Oct 2005

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Singer, D. E., Kiwanuka, N., Serwadda, D., Nalugoda, F., Hird, L., Bulken-Hoover, J., Kigozi, G., Malia, J. A., Calero, E. K., Sateren, W., Robb, M. L., Wabwire-Mangen, F., Wawer, M., Gray, R. H., Sewankambo, N., Birx, D. L., & Michael, N. L. (2005). Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays. Journal of Clinical Microbiology, 43(10), 5312-5315. https://doi.org/10.1128/JCM.43.10.5312-5315.2005

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title = "Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays",

abstract = "We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100\% and a specificity of 98.9\% (95\% confidence interval, 98.6\% to 99.3\%).",

author = "Singer, \{Darrell E.\} and Noah Kiwanuka and David Serwadda and Fred Nalugoda and Linda Hird and Jamie Bulken-Hoover and Godfrey Kigozi and Malia, \{Jennifer A.\} and Calero, \{Eva K.\} and Warren Sateren and Robb, \{Merlin L.\} and Fred Wabwire-Mangen and Maria Wawer and Gray, \{Ronald H.\} and Nelson Sewankambo and Birx, \{Deborah L.\} and Michael, \{Nelson L.\}",

year = "2005",

month = oct,

doi = "10.1128/JCM.43.10.5312-5315.2005",

language = "English",

volume = "43",

pages = "5312--5315",

journal = "Journal of Clinical Microbiology",

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Singer, DE, Kiwanuka, N, Serwadda, D, Nalugoda, F, Hird, L, Bulken-Hoover, J, Kigozi, G, Malia, JA, Calero, EK, Sateren, W, Robb, ML, Wabwire-Mangen, F, Wawer, M, Gray, RH, Sewankambo, N, Birx, DL & Michael, NL 2005, 'Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays', Journal of Clinical Microbiology, vol. 43, no. 10, pp. 5312-5315. https://doi.org/10.1128/JCM.43.10.5312-5315.2005

TY - JOUR

T1 - Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

AU - Singer, Darrell E.

AU - Kiwanuka, Noah

AU - Serwadda, David

AU - Nalugoda, Fred

AU - Hird, Linda

AU - Bulken-Hoover, Jamie

AU - Kigozi, Godfrey

AU - Malia, Jennifer A.

AU - Calero, Eva K.

AU - Sateren, Warren

AU - Robb, Merlin L.

AU - Wabwire-Mangen, Fred

AU - Wawer, Maria

AU - Gray, Ronald H.

AU - Sewankambo, Nelson

AU - Birx, Deborah L.

AU - Michael, Nelson L.

PY - 2005/10

Y1 - 2005/10

N2 - We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

AB - We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

UR - https://www.scopus.com/pages/publications/26944448208

U2 - 10.1128/JCM.43.10.5312-5315.2005

DO - 10.1128/JCM.43.10.5312-5315.2005

M3 - Article

C2 - 16208006

AN - SCOPUS:26944448208

SN - 0095-1137

VL - 43

SP - 5312

EP - 5315

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 10

ER -

Use of stored serum from Uganda for development and evaluation of a human immunodeficiency virus type 1 testing algorithm involving multiple rapid immunoassays

Abstract

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