Volumetric muscle loss: a bibliometric analysis of a decade of progress

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The consequences of military conflict, accidents, and diseases have led to the definition - and subsequent study - of the pathological condition now known as volumetric muscle loss (VML). VML is a significant injury to skeletal muscle tissue on a scale that is endogenously irrecoverable and leads to chronic functional deficits and long-term disability. Currently, there lacks a definitive approach to meaningfully restore the tissue and function lost by those afflicted, ushering a need for scientific activities and associated funding to both facilitate a deeper understanding of the pathobiology of VML as well as to develop and assess clinically relevant therapeutics and treatment strategies. Thereby, evaluation of the VML field is crucial to gauging the return on resource expenditures and to understand the evolution of the field to guide future directions. This article presents a bibliometric analysis of publicly available data to explore the growth of the VML field since its genesis and to highlight its prosperity through its expanding literature, its development and evaluation of promising treatment strategies, rising financial investments, and innovation. Together, the bibliometric analysis reveals the field of VML as an emergent research focus that is productive and translational.

Original languageEnglish
JournalTissue Engineering - Part B: Reviews
StateE-pub ahead of print - 7 Dec 2022


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